← Back to Search

Local Anesthetic

Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery

Phase 2
Waitlist Available
Led By Poovendran Saththasivam, MD
Research Sponsored by The Guthrie Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at end of surgery
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing whether it's better to have a single shot of long-acting local anesthetic or a catheter infusion of local anesthetic during VAT surgery.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 72 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 72 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Numerical Rated Pain Scale (NRP)
Secondary study objectives
Adverse events frequency
Incentive spirometry changes from preoperative baseline to 3 days post-operative
Length of hospital stay
+4 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Single Shot Liposomal Bupivacaine (EXPAREL®)/BupivacaineExperimental Treatment1 Intervention
Single Shot Liposomal Bupivacaine (EXPAREL®)/Bupivacaine for erector spinae block as local anesthetic
Group II: Continuous catheter infusion ropivacaineActive Control1 Intervention
Ropivacaine (0.5% bolus followed by 0.2% infusion) using a continuous catheter for erector spinae plane block as local anesthetic

Find a Location

Who is running the clinical trial?

The Guthrie ClinicLead Sponsor
26 Previous Clinical Trials
1,729 Total Patients Enrolled
Poovendran SaththasivamLead Sponsor
Poovendran Saththasivam, MDPrincipal InvestigatorThe Guthrie Clinic
~15 spots leftby Dec 2025