Your session is about to expire
← Back to Search
Other
Choline for Cardiovascular Risk
N/A
Waitlist Available
Led By Kevin Davy, PhD
Research Sponsored by Virginia Polytechnic Institute and State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
* 18-65 years old, healthy, non-smoking weight stable for previous 6 months (±2.0 kg), BMI\<35 kg/m\^2, verbal and written informed consent, approved for participation by study medical director (Jose Rivero, M.D.)
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 45-minute measurement in laboratory
Summary
This trial is studying how well trimethylamine-N-oxide (TMAO) works in improving vascular function in people with stable cardiovascular disease.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 45-minute measurement in laboratory
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~45-minute measurement in laboratory
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in brachial artery function after supplementation
Secondary study objectives
Change in arterial stiffness after supplementation
Change in gut-mediated TMAO levels after supplementation
Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Short Term Choline SupplementationExperimental Treatment1 Intervention
Participants will be asked to consume 1000 mg of choline bitartrate for 4 weeks prior to and during the testing period.
Group II: Short Term Placebo SupplementationPlacebo Group1 Intervention
Participants will be asked to consume 1000 mg of placebo (maltodextrin) for 4 weeks prior to and during the testing period.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Choline
2018
Completed Phase 4
~620
Find a Location
Who is running the clinical trial?
Virginia Polytechnic Institute and State UniversityLead Sponsor
153 Previous Clinical Trials
25,063 Total Patients Enrolled
3 Trials studying Cardiovascular Risk
56 Patients Enrolled for Cardiovascular Risk
Kevin Davy, PhDPrincipal Investigator - Virginia Polytechnic Institute and State University
Virginia Polytechnic Institute and State University
4 Previous Clinical Trials
98 Total Patients Enrolled
3 Trials studying Cardiovascular Risk
56 Patients Enrolled for Cardiovascular Risk
Share this study with friends
Copy Link
Messenger