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Dosimetry Group for Gynecologic Cancers

Phase 2
Waitlist Available
Led By Steve Cho, MD
Research Sponsored by University of Wisconsin, Madison
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 1 day
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing how well PSMA PET and MR Imaging can detect cancer cells in people with gynecologic cancer.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 1 day
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 day for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Diagnostic Accuracy
Secondary study objectives
Biodistribution of PSMA Measured by SUVmax in Cancer Tissue
Biodistribution of PSMA Measured by SUVmax in Normal Tissue
Radiodosimetry of PSMA
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: Patient GroupExperimental Treatment1 Intervention
The patient group will consist of women with suspected gynecological cancers who are undergoing hysterectomy and salpingo-oophorectomy. Women will receive standard of care PSMA-based 18F-DCFPyL tracer and PET/MR imaging. n=40
Group II: Healthy Control Non-Dosimetry GroupExperimental Treatment1 Intervention
The control group will consists of women with no imaging evidence of gynecological cancer, who are undergoing hysterectomy and salpingo-oophorectomy. Women will receive PSMA-based 18F-DCFPyL tracer and PET/MR imaging. n=6
Group III: Dosimetry GroupExperimental Treatment1 Intervention
Women with or without suspected gynecological cancer. Women will receive PSMA-based 18F-DCFPyL tracer and PET/CT imaging, PET/MR imaging as needed. n=6

Find a Location

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,230 Previous Clinical Trials
3,199,810 Total Patients Enrolled
1 Trials studying Gynecologic Cancers
75 Patients Enrolled for Gynecologic Cancers
Steve Cho, MDPrincipal InvestigatorUniversity of Wisconsin, Madison
4 Previous Clinical Trials
24 Total Patients Enrolled
Elizabeth Sadowski, MDPrincipal InvestigatorUniversity of Wisconsin, Madison
1 Previous Clinical Trials
1,340 Total Patients Enrolled
~2 spots leftby Nov 2025
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