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Behavioral Intervention

Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit) (Tweet2Quit Trial)

Phase 2
Waitlist Available
Led By Connie (Cornelia) Pechmann, PhD, MBA, MS
Research Sponsored by University of California, Irvine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 month
Awards & highlights
No Placebo-Only Group

Summary

This trial tests Tweet2Quit, an online support program for quitting smoking. It focuses on whether women benefit more from women-only groups compared to mixed-gender groups. The program provides peer support and automatic messages to help participants stay engaged and quit smoking. Tweet2Quit is a novel Twitter-delivered intervention for smoking cessation that sends regular automated communications to small, private, self-help groups to encourage high-quality, online, peer-to-peer discussions.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 month for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Percentage of Participants With a 6-month Sustained Abstinence
Secondary study objectives
Percentage of participants with a 3-month sustained abstinence
Other study objectives
Percentage of participants with a 7-Day point prevalence abstinence

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: NRT + Web Guide + Tweet2Quit-WomenExperimental Treatment3 Interventions
Experimental: NRT + Web Guide + Tweet2Quit-Women NCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges) plus assignment to a women-only Tweet2Quit group
Group II: NRT + Web Guide + Tweet2Quit-CoedExperimental Treatment3 Interventions
NCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges) plus assignment to a coed Tweet2Quit group
Group III: Initial Pilot Group (NRT + Web Guide + Tweet2Quit-Coed)Experimental Treatment3 Interventions
The initial pilot group was run to check technology functionality and user acceptance; it was not included in outcome assessments. These participants received NCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges) plus assignment to a coed Tweet2Quit group.
Group IV: NRT + Web GuideActive Control2 Interventions
NCI Smokefree.gov plus 8 weeks of combination NRT (nicotine patch plus gum/lozenges)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tweet2Quit
2016
Completed Phase 2
~980
NRT
2016
Completed Phase 2
~1280
Web Guide
2016
Completed Phase 2
~980

Find a Location

Who is running the clinical trial?

Stanford UniversityOTHER
2,484 Previous Clinical Trials
17,515,141 Total Patients Enrolled
University of California, IrvineLead Sponsor
566 Previous Clinical Trials
1,932,098 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,938 Previous Clinical Trials
41,022,190 Total Patients Enrolled
Connie (Cornelia) Pechmann, PhD, MBA, MSPrincipal InvestigatorUniversity of California, Irvine
Judith J Prochaska, PhD, MPHPrincipal InvestigatorStanford University
5 Previous Clinical Trials
986 Total Patients Enrolled
~107 spots leftby Dec 2025