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Glucagon-like peptide-1 receptor agonist

Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy (RAISE-KT Trial)

Wilkes-Barre, PA
Phase 3
Waitlist Available
Led By Alex R Chang, MD, MS
Research Sponsored by Geisinger Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 9 months
Awards & highlights
Pivotal Trial

Summary

This trial looks at whether semaglutide, a diabetes medication, can help people with diabetes and kidney disease who are overweight or obese.

See full description
Eligible Conditions
  • Diabetic Kidney Disease
  • Diabetes
  • Obesity
  • Chronic kidney disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 9 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Kidney Transplant Eligibility
Secondary study objectives
Change in BMI
Change in Body Fat Percentage
Change in Hemoglobin A1c (HgbA1c)
+4 more
Other study objectives
All-cause Hospitalizations
Cardiovascular Disease (CVD) Events
Change in Albuminuria Among Subset of Participants Without End-stage Kidney Disease
+15 more

Awards & Highlights

Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: SemaglutideActive Control1 Intervention
This arm will receive semaglutide.
Group II: PlaceboPlacebo Group1 Intervention
This arm will receive placebo.

Find a Location

Closest Location:Geisinger Wyoming Valley· Wilkes-Barre, PA

Who is running the clinical trial?

Geisinger ClinicLead Sponsor
158 Previous Clinical Trials
1,976,279 Total Patients Enrolled
Alex R Chang, MD, MSPrincipal InvestigatorGeisinger Clinic
1 Previous Clinical Trials
31 Total Patients Enrolled
~3 spots leftby Mar 2026
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