← Back to Search

Vitamin B3 Supplement

Niagen for Psoriasis

N/A
Waitlist Available
Led By Michael N Sack, M.D.
Research Sponsored by National Heart, Lung, and Blood Institute (NHLBI)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and day 28

Summary

This trial tests whether a vitamin B3 supplement can help people with mild to moderate psoriasis. Participants will take the supplement for several weeks. The goal is to see if the supplement can reduce the activity of immune cells that cause skin inflammation.

Eligible Conditions
  • Psoriasis
  • High cholesterol
  • Metabolic Syndrome
  • Cardiovascular Disease
  • Obesity

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and day 28
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and day 28 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Mean Change in the TH17 Cell Cytokine IL-17 Secretion in Response to T-cell Differentiation

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Participants with mild to moderate Psoriasis receiving Nicotinamide RibosideExperimental Treatment1 Intervention
Participants with mild to moderate Psoriasis receiving Nicotinamide Riboside Chloride 500mg (2 capsules) twice daily by mouth for 28 days.
Group II: Participants with mild to moderate Psoriasis receiving PlaceboPlacebo Group1 Intervention
Participants with mild to moderate Psoriasis receiving placebo (2 capsules) twice daily by mouth for 28 days.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Niagen
2020
Completed Phase 4
~170

Find a Location

Who is running the clinical trial?

National Heart, Lung, and Blood Institute (NHLBI)Lead Sponsor
3,933 Previous Clinical Trials
47,791,007 Total Patients Enrolled
5 Trials studying Psoriasis
561 Patients Enrolled for Psoriasis
Michael N Sack, M.D.Principal InvestigatorNational Heart, Lung, and Blood Institute (NHLBI)
13 Previous Clinical Trials
9,209 Total Patients Enrolled
3 Trials studying Psoriasis
429 Patients Enrolled for Psoriasis
~6 spots leftby Nov 2025