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Anti-tumor antibiotic

Hepatic Artery Infusion Chemotherapy for Liver Cancer

Phase 2
Waitlist Available
Led By Hui-Chuan Sun, MD&PhD
Research Sponsored by Hui-Chuan Sun
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 2 year
Awards & highlights
All Individual Drugs Already Approved
Approved for 5 Other Conditions
No Placebo-Only Group

Summary

There are limited treatment options for patients with unresectable hepatocellular carcinoma (HCC) who failed to the combination therapy with targeted agents plus anti-PD-1/PD-L1. Hepatic artery infusion chemotherapy (HAIC) had shown potent antitumor effects in single-centered studies when was used as first-line therapy. However, HAIC was not used as second or third-line therapy.

Eligible Conditions
  • Liver Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 2 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Objective response of intrahepatic lesions
Secondary study objectives
Overall survival
Progression free survival
Ratio of R0 resection
+3 more

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Hepatic Artery Infusion ChemotherapyExperimental Treatment1 Intervention
Subjects assigned to this arm will receive chemotherapy via catheterizations placed into the hepatic artery.

Find a Location

Who is running the clinical trial?

Hui-Chuan SunLead Sponsor
2 Previous Clinical Trials
150 Total Patients Enrolled
Hui-Chuan Sun, MD&PhDPrincipal InvestigatorFudan University
2 Previous Clinical Trials
86 Total Patients Enrolled
~11 spots leftby Dec 2025
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