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DCS for Obsessive-Compulsive Disorder (DCS Trial)

Phase 2
Waitlist Available
Led By Lindsey Bergman
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up post-treatment (study day 9)
Awards & highlights
Approved for 5 Other Conditions
All Individual Drugs Already Approved

Summary

This trial is testing whether a medication called D-cycloserine can make therapy more effective for children and teens with OCD. The medication is given before therapy sessions to help the brain learn that feared objects or situations are safe. Researchers hope this will improve treatment outcomes for kids who don't fully respond to standard therapy.

Eligible Conditions
  • Obsessive-Compulsive Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~post-treatment (study day 9)
This trial's timeline: 3 weeks for screening, Varies for treatment, and post-treatment (study day 9) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
OCD symptom severity on the Children's Yale Brown Obsessive Compulsive Scale (CYBOCS)

Awards & Highlights

Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: DCSActive Control1 Intervention
Participant takes one pill of D-Cycloserine a day 4 times weekly immediately preceding the treatment session for two weeks of treatment (4 sessions weekly).
Group II: PlaceboPlacebo Group1 Intervention
Participant takes one pill of placebo a day 4 times weekly immediately preceding the treatment session for two weeks of treatment (4 sessions weekly).

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,564 Previous Clinical Trials
10,262,607 Total Patients Enrolled
10 Trials studying Obsessive-Compulsive Disorder
615 Patients Enrolled for Obsessive-Compulsive Disorder
Lindsey BergmanPrincipal InvestigatorUniversity of California, Los Angeles
~2 spots leftby Nov 2025
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