~99 spots leftby Apr 2026

Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes

Recruiting in Palo Alto (17 mi)
+174 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 3
Waitlist Available
Sponsor: Mannkind Corporation
No Placebo Group
Pivotal Trial (Near Approval)
Prior Safety Data

Trial Summary

What is the purpose of this trial?

Pulmonary Safety in Diabetics with T/I

Research Team

Eligibility Criteria

Inclusion Criteria

Nonsmoking
Body mass index <42 kg/m2
FEV1 greater than or equal to 70% of predicted , DLco and TLC greater than or equal to 80% of predicted at screening
See 5 more

Treatment Details

Interventions

  • Technosphere® Insulin Inhalation Powder (Insulin)
Participant Groups
3Treatment groups
Experimental Treatment
Active Control
Group I: Usual careExperimental Treatment1 Intervention
Usual care
Group II: TI Inhalation PowderExperimental Treatment1 Intervention
Technosphere® Insulin Inhalation Powder
Group III: Non-diabetesActive Control1 Intervention
Subjects without abnormalities in glucose control (Note: Hypoglycemia and HbA1c were not reported for this group)

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Diabetes Care CenterSalinas, CA
Cedar-Crosse Research CenterChicago, IL
University of Texas Southwestern Medical CenterDallas, TX
Clinical Research Department Wenatchee Valley Medical CenterWenatchee, WA
More Trial Locations
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Who Is Running the Clinical Trial?

Mannkind Corporation

Lead Sponsor

Trials
61
Patients Recruited
8,400+