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Procedure
EPR for Traumatic Cardiac Arrest (EPR-CAT Trial)
Phase 2
Waitlist Available
Led By Samuel A Tisherman, MD
Research Sponsored by University of Maryland, Baltimore
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group
Summary
This trial is testing a new method of saving people who have suffered cardiac arrest from bleeding.
Eligible Conditions
- Heart Attack
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Emergency preservation and resuscitationExperimental Treatment1 Intervention
These subjects would undergo the complete EPR protocol, including rapid induction of hypothermia, resuscitative surgery, and resuscitation with cardiopulmonary bypass.
Group II: Concurrent controlsActive Control1 Intervention
These subjects would undergo standard resuscitative efforts.
Find a Location
Who is running the clinical trial?
University of Maryland, BaltimoreLead Sponsor
713 Previous Clinical Trials
379,472 Total Patients Enrolled
Cook County HealthOTHER_GOV
46 Previous Clinical Trials
16,817 Total Patients Enrolled
John H. Stroger HospitalOTHER
42 Previous Clinical Trials
13,035 Total Patients Enrolled
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Eligibility Criteria:
This trial includes the following eligibility criteria:- The person showed no signs of life for more than 5 minutes before emergency medical procedures were started.You have a severe injury that is not survivable.You have signs of a serious head injury, like a major change in the shape of your face or head.Your heart has stopped beating.A quick evaluation of the injuries shows severe damage to a lot of body areas or blunt trauma to many parts of the body.You have a serious injury with a lot of bleeding.The person shows signs of life at the scene, like having a pulse, breathing, moving on their own, or reacting to light with their pupils.You didn't have a pulse for less than 5 minutes before reaching the emergency room or while in the emergency room or operating room.If you had emergency chest surgery and did not regain a pulse in the neck arteries right away.
Research Study Groups:
This trial has the following groups:- Group 1: Concurrent controls
- Group 2: Emergency preservation and resuscitation
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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