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Brachytherapy

Vaginal Cuff Brachytherapy for Endometrial Cancer

Phase 2
Waitlist Available
Led By Scott McMeekin, MD
Research Sponsored by University of Oklahoma
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Summary

The purpose of this study is to determine the progression-free survival of patients with surgically staged, Stage I-II papillary serous, clear cell, or endometrioid carcinomas with high-intermediate risk factors treated by vaginal cuff brachytherapy followed by chemotherapy.

Eligible Conditions
  • Endometrial Cancer
  • Serous Cystadenocarcinoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Side effects data

From 2021 Phase 2 trial • 39 Patients • NCT03189446
9%
Taxol Reaction
6%
Fatigue
6%
Diarrhea
6%
Anemia
6%
Peripheral Neuropathy
100%
80%
60%
40%
20%
0%
Study treatment Arm
Vaginal Cuff Brachytherapy + Chemotherapy

Trial Design

1Treatment groups
Experimental Treatment
Group I: Vaginal Cuff BrachytherapyExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vaginal Cuff Brachytherapy
2017
Completed Phase 2
~70

Find a Location

Who is running the clinical trial?

University of OklahomaLead Sponsor
466 Previous Clinical Trials
91,200 Total Patients Enrolled
6 Trials studying Endometrial Cancer
318 Patients Enrolled for Endometrial Cancer
Scott McMeekin, MDPrincipal InvestigatorUniversity of Oklahoma
~1 spots leftby Sep 2025