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Platelet-rich Plasma

PRP for Eyebrow Hypotrichosis and Alopecia Areata

Phase 2
Recruiting
Led By Murad Alam
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years

Summary

This trial is to test whether autologous platelet-rich plasma can help treat eyebrow hypotrichosis, or insufficient eyebrow hair growth. 40 people will be randomly chosen to either receive the plasma injections or a placebo saline solution. The trial will last 9 months.

Who is the study for?
This trial is for adults aged 18-85 in the Chicago area with mild to moderate eyebrow thinning who are healthy and can give informed consent. It's not for those with uncontrolled diseases affecting hair growth, recent use of certain hair growth drugs, significant blood disorders, genetic conditions impacting fibroblasts or collagen, pregnant/breastfeeding individuals, or those unable to follow the study protocol.
What is being tested?
The trial tests if injections of platelet-rich plasma (PRP) help people with sparse eyebrows compared to saline (saltwater) injections. About 40 participants will be randomly chosen to receive either PRP or saline over a period of nine months in this pilot study aimed at assessing procedure feasibility.
What are the potential side effects?
While specific side effects aren't listed here, common ones from similar procedures may include discomfort at injection sites, infection risk, bruising or bleeding especially in those with clotting disorders. The safety profile will be closely monitored throughout the study.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Platelet-Rich PlasmaExperimental Treatment1 Intervention
Participants will receive intradermal injections of 2-3mL autologous PRP to eyebrows.Three treatments will be performed 1 month apart.
Group II: Placebo (sterile saline)Placebo Group1 Intervention
Participants will receive intradermal injections of 2-3mL sterile saline to eyebrows.Three treatments will be performed 1 month apart.

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,652 Previous Clinical Trials
961,485 Total Patients Enrolled
Murad AlamPrincipal Investigator - Northwestern University
Northwestern Memorial Hospital
Yale University School Of Medicine (Medical School)
Ny And Presby Hospital (Residency)

Media Library

Platelet-rich Plasma (Platelet-rich Plasma) Clinical Trial Eligibility Overview. Trial Name: NCT04018859 — Phase 2
Eyebrow Hypotrichosis Research Study Groups: Placebo (sterile saline), Platelet-Rich Plasma
Eyebrow Hypotrichosis Clinical Trial 2023: Platelet-rich Plasma Highlights & Side Effects. Trial Name: NCT04018859 — Phase 2
Platelet-rich Plasma (Platelet-rich Plasma) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04018859 — Phase 2
~5 spots leftby Dec 2025
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