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Aminopeptidase inhibitor

Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia

Phase 2
Waitlist Available
Research Sponsored by Chroma Therapeutics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up protocol-mandated visits every 12 weeks
Awards & highlights
No Placebo-Only Group

Summary

The purpose of this study is to evaluate the long-term efficacy and safety profile of tosedostat in elderly patients suffering from refractory or relapsed Acute Myeloid Leukemia.

Eligible Conditions
  • Acute Myeloid Leukemia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~protocol mandated visits every 12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and protocol mandated visits every 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Safety and Tolerability of extended treatment with tosedostat
Secondary study objectives
Efficacy of extended treatment with tosedostat

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: TosedostatExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tosedostat
Not yet FDA approved

Find a Location

Who is running the clinical trial?

Chroma TherapeuticsLead Sponsor
9 Previous Clinical Trials
344 Total Patients Enrolled
~2 spots leftby Dec 2025