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Cannabidiol for Opioid Use Disorder (CURB Trial)

Phase 2
Waitlist Available
Led By Joji Suzuki, M.D.
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-exposure (visit 2, which is day 2 of the 5-day study) and post-exposure (visit 3, which is day 5 of the 5-day study)
Awards & highlights

Summary

This trial will study whether CBD can help reduce cravings in people with opioid addiction who are also taking buprenorphine.

Eligible Conditions
  • Opioid Use Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-exposure (visit 2, which is day 2 of the 5-day study) and post-exposure (visit 3, which is day 5 of the 5-day study)
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-exposure (visit 2, which is day 2 of the 5-day study) and post-exposure (visit 3, which is day 5 of the 5-day study) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in Cue-induced Cravings and Anxiety After 3 Days of Cannabidiol Administration

Trial Design

1Treatment groups
Experimental Treatment
Group I: CannabidiolExperimental Treatment1 Intervention
As this is a single-arm, open-label study, all subjects will receive the interventional arm, specifically 600mg of oral cannabidiol once daily for 3 consecutive days.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cannabidiol 600mg
2020
Completed Phase 2
~10

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor
1,628 Previous Clinical Trials
11,474,632 Total Patients Enrolled
Joji Suzuki, M.D.Principal Investigator - Brigham and Women's Hospital
Brigham & Women's Faulkner Hospital, Brigham & Women's Hospital
Boston University School Of Medicine (Medical School)
Boston Medical Center (Residency)
~2 spots leftby Sep 2025
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