Patupilone Versus Doxorubicin in Patients With Ovarian, Primary Fallopian, or Peritoneal Cancer
Recruiting in Palo Alto (17 mi)
+147 other locations
Age: 18+
Sex: Female
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 3
Waitlist Available
Sponsor: Novartis Pharmaceuticals
No Placebo Group
Pivotal Trial (Near Approval)
Prior Safety Data
Trial Summary
What is the purpose of this trial?
The objective of this study is to assess the safety and efficacy of patupilone compared to pegylated liposomal doxorubicin. Additionally, this study will assess the ability of patupilone to extend the survival time and potential beneficial effects in women who have nonresponsive or recurrent ovarian, primary fallopian, or primary peritoneal cancer.
Eligibility Criteria
Inclusion Criteria
18 years of age or older
Confirmed diagnosis of ovarian, fallopian or peritoneal cancer
No more than three chemotherapy regimens
See 1 more
Treatment Details
Interventions
- Doxorubicin (Anthracycline)
- Patupilone (Epothilone)
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: PatupiloneExperimental Treatment1 Intervention
Group II: doxorubicinActive Control1 Intervention
Doxorubicin is already approved in United States, European Union, Canada, Japan for the following indications:
🇺🇸 Approved in United States as Adriamycin for:
- Breast cancer
- Ovarian cancer
- Bladder cancer
- Lymphomas
- Leukemias
- Multiple myeloma
- Kaposi's sarcoma
- Soft tissue sarcomas
🇪🇺 Approved in European Union as Doxorubicin for:
- Breast cancer
- Ovarian cancer
- Bladder cancer
- Lymphomas
- Leukemias
- Multiple myeloma
- Kaposi's sarcoma
- Soft tissue sarcomas
🇨🇦 Approved in Canada as Doxorubicin for:
- Breast cancer
- Ovarian cancer
- Bladder cancer
- Lymphomas
- Leukemias
- Multiple myeloma
- Kaposi's sarcoma
- Soft tissue sarcomas
🇯🇵 Approved in Japan as Doxorubicin for:
- Breast cancer
- Ovarian cancer
- Bladder cancer
- Lymphomas
- Leukemias
- Multiple myeloma
- Kaposi's sarcoma
- Soft tissue sarcomas
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
UC Davis Cancer CenterSacramento, CA
Gynecologic Oncology associatesNewport Beach, CA
LAC & USC Women's & Children's HospitalLos Angeles, CA
Indiana University Cancer Center/Indiana UNiversity Melvin & Bren Simon Cancer CenterIndianapolis, IN
More Trial Locations
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Who Is Running the Clinical Trial?
Novartis PharmaceuticalsLead Sponsor