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Imaging

Active Surveillance Magnetic Resonance Imaging Study (ASIST Trial)

Phase 3
Waitlist Available
Led By Laurence Klotz, MD
Research Sponsored by Canadian Urology Research Consortium
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Pivotal Trial
No Placebo-Only Group

Summary

This is a multi-centre, prospective, randomized phase III trial to determine if multi-parametric Magnetic Resonance Imaging (MRI) can improve selection of patients eligible for active surveillance through better detection of clinically significant cancer.

Eligible Conditions
  • Prostate Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MRI Assisted TRUS guided biopsyExperimental Treatment1 Intervention
Group II: TRUS guided biopsyActive Control1 Intervention

Find a Location

Who is running the clinical trial?

OICRUNKNOWN
3 Previous Clinical Trials
45 Total Patients Enrolled
1 Trials studying Prostate Cancer
5 Patients Enrolled for Prostate Cancer
EigenOTHER
2 Previous Clinical Trials
307 Total Patients Enrolled
Canadian Urology Research ConsortiumLead Sponsor
6 Previous Clinical Trials
941 Total Patients Enrolled
4 Trials studying Prostate Cancer
615 Patients Enrolled for Prostate Cancer
Laurence Klotz, MDPrincipal InvestigatorCanadian Urology Research Consortium
7 Previous Clinical Trials
1,308 Total Patients Enrolled
6 Trials studying Prostate Cancer
1,164 Patients Enrolled for Prostate Cancer
~18 spots leftby Dec 2025
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