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Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study

N/A
Waitlist Available
Led By Renuka M George, MD
Research Sponsored by Medical University of South Carolina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 hours
Awards & highlights
No Placebo-Only Group

Summary

This trial compares two pain relief methods, TAP and QL blocks, for patients undergoing laparoscopic abdominal surgeries. These methods involve injecting numbing medication into specific areas of the abdomen to block pain. The goal is to see which method provides better pain control and reduces the need for opioid medications. TAP blocks have been shown to successfully reduce pain and opioid consumption after various types of surgeries, including abdominal and urological procedures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Dermatomal Mapping

Side effects data

From 2018 Phase 2 trial • 60 Patients • NCT03007966
41%
Nausea
21%
Vomiting
7%
Itching
100%
80%
60%
40%
20%
0%
Study treatment Arm
Ilioinguinal / Iliohypogastric Block
Quadratus Lumborum Block

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Quadratus Lumborum BlockExperimental Treatment1 Intervention
Quadratus lumborum nerve block
Group II: Control - Transversus Abdominus Plane BlockActive Control1 Intervention
Standardized ERAS regional nerve block
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Quadratus Lumborum Block
2020
Completed Phase 2
~1000

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
977 Previous Clinical Trials
7,400,805 Total Patients Enrolled
Renuka M George, MDPrincipal InvestigatorMedical University of South Carolina
~24 spots leftby Dec 2025
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