← Back to Search

Monoclonal Antibodies

Dupilumab for Asthma

Phase 4
Waitlist Available
Led By Yvonne Huang, MD
Research Sponsored by University of Michigan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 month, 4 months
Awards & highlights

Study Summary

This trial is investigating whether the study drug, dupilumab, can improve the health of participants lungs, boost immune response, as well as improve quality of life for people with severe asthma.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month, 4 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month, 4 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in beta-diversity of respiratory microbiota
Change in beta-diversity of stool microbiota
Change in relative abundances of microbiota members
+3 more
Secondary outcome measures
Asthma Control Test (ACT)
Change in Fractional exhaled nitric oxide (FeNO)
Adrenal Cortex Hormones
+5 more

Side effects data

From 2021 Phase 4 trial • 188 Patients • NCT04033367
9%
Conjunctivitis
7%
Headache
3%
Dermatitis Atopic
2%
Nasopharyngitis
1%
Accidental Overdose
1%
Drug Hypersensitivity
1%
Polyarthritis
100%
80%
60%
40%
20%
0%
Study treatment Arm
DB Period: Placebo
DB Period: Dupilumab
OLE Period: Dupilumab/Dupilumab
OLE Period: Placebo/Dupilumab

Trial Design

1Treatment groups
Experimental Treatment
Group I: DupilumabExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Dupilumab
2017
Completed Phase 4
~12230

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor
1,810 Previous Clinical Trials
6,385,090 Total Patients Enrolled
17 Trials studying Asthma
5,238 Patients Enrolled for Asthma
Regeneron PharmaceuticalsIndustry Sponsor
628 Previous Clinical Trials
382,227 Total Patients Enrolled
28 Trials studying Asthma
11,972 Patients Enrolled for Asthma
Yvonne Huang, MDPrincipal InvestigatorUniversity of Michigan
~5 spots leftby Jun 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top