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Beta Blocker

Rate Control in Atrial Fibrillation

Phase 4
Waitlist Available
Led By Pallavi Bellamkonda, MBBS
Research Sponsored by Creighton University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 weeks
Awards & highlights
Approved for 10 Other Conditions
Drug Has Already Been Approved
All Individual Drugs Already Approved
Pivotal Trial
No Placebo-Only Group

Summary

This study will evaluate the efficacy of metoprolol tartrate compared to carvedilol on heart rate control in patients with atrial fibrillation and a rapid ventricular rate.

Eligible Conditions
  • Atrial Fibrillation

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Resting heart rate

Awards & Highlights

Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.
Drug Has Already Been Approved
The FDA has already approved this drug, and is just seeking more data.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Metoprolol tartrateExperimental Treatment1 Intervention
Metoprolol tartrate BID for 2 weeks
Group II: CarvedilolExperimental Treatment1 Intervention
carvedilol BID for 2 weeks
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Carvedilol
FDA approved
Metoprolol
FDA approved

Find a Location

Who is running the clinical trial?

Creighton UniversityLead Sponsor
126 Previous Clinical Trials
25,706 Total Patients Enrolled
5 Trials studying Atrial Fibrillation
485 Patients Enrolled for Atrial Fibrillation
Pallavi Bellamkonda, MBBSPrincipal InvestigatorCreighton University
~2 spots leftby Jan 2026
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