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Interventional: Cyanoacrylate Application for Oral Surgery

Phase 4
Waitlist Available
Led By Penny Hatzimanolakis, DipDH, BDSc, MSc, RDH
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Summary

Periodontal disease is a gum infection caused by plaque on teeth containing both bacteria and calculus (hard) deposits. These need to be removed on a regular basis to maintain gum health and to prevent teeth weakening. A routine cleaning procedure, scaling/root planing, is accompanied with post-operative soft tissue tenderness and teeth sensitivity making oral hygiene maintenance difficult during wound healing. The need for novel therapeutic approaches, such as cyanoacrylate adhesives, has been identified. It has been hypothesized that its application may provide comfort and assist patients with their daily oral self-care procedures following teeth cleaning.

Eligible Conditions
  • Oral Surgery
  • Pain
  • Gum Disease
  • Tissue Adhesive
  • Dental Scaling
  • Wound Healing

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Interventional: Cyanoacrylate ApplicationExperimental Treatment1 Intervention
Application of cyanoacrylate adhesive to one quadrant of mouth
Group II: Control: Absence of Cyanoacrylate ApplicationActive Control1 Intervention
No application of cyanoacrylate adhesive to the other quadrant of mouth

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor
1,451 Previous Clinical Trials
2,483,170 Total Patients Enrolled
Penny Hatzimanolakis, DipDH, BDSc, MSc, RDHPrincipal InvestigatorUniversity of British Columbia
~2 spots leftby Sep 2025