Chlorhexidine for Recurrent Urinary Tract Infections

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 4

Recruiting

Sponsor: Oregon Health and Science University

No Placebo Group

Prior Safety Data

Approved in 5 Jurisdictions

Trial Summary

What is the purpose of this trial?A two-arm randomized control trial evaluating rates of urinary tract infection in post-menopausal women on vaginal estrogen with recurrent urinary tract infections.

Eligibility Criteria

This trial is for post-menopausal women who are using vaginal estrogen and have had multiple urinary tract infections. Specific eligibility details aren't provided, but typically participants must meet certain health standards and not have conditions that could interfere with the study.

Inclusion Criteria

I am a woman aged 55-89 and have gone through menopause.

No post-menopausal bleeding

Ready access to email and internet

+4 more

Exclusion Criteria

Non-English speaking

I have had serious urinary tract infections before.

My condition is a severe pelvic organ prolapse.

+10 more

Participant Groups

The study is testing whether rinsing with Chlorhexidine or Sterile Water affects the rate of recurrent urinary tract infections in the target group. It's a two-arm trial, meaning there are two groups: one using Chlorhexidine and one using Sterile Water.

2Treatment groups

Experimental Treatment

Active Control

Group I: Chlorhexidine LavageExperimental Treatment1 Intervention

2% chlorhexidine perineal lavage following defecation

Group II: Sterile Water LavageActive Control1 Intervention

Sterile water perineal lavage following defecation

Chlorhexidine is already approved in European Union, United States, Canada, Japan, Australia for the following indications:

🇪🇺 Approved in European Union as Chlorhexidine for: