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standard CPET with in-line filter for Transmission-Based Precautions

N/A
Waitlist Available
Led By Jie Li, PhD
Research Sponsored by Rush University Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 45 minutes
Awards & highlights

Summary

Due to the concerns of virus transmission during COVID-19 pandemic, multiple respiratory societies postpone or limit pulmonary function test, especially cardiopulmonary exercise test (CPET), as patients may generate large amount of aerosol particles during test but it is conventionally performed without filter. This study aims to investigate the effects of reducing aerosol particle concentrations in the room air during CPET by placing an inline filter, and to assess the effects of filter on the physiologic responses during CPET.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~45 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 45 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The Peak Aerosol Particle Concentrations During CPET With a Filter and Without a Filter
The Peak Carbon Dioxide Output With and Without a Filter
The Peak Minute Ventilation With and Without a Filter
+1 more
Secondary outcome measures
The Peak Heart Rate With and Without a Filter

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: standard CPET with in-line filterExperimental Treatment1 Intervention
An in-line filter will be placed on the mouthpiece during standard CPET
Group II: standard CPETActive Control1 Intervention
Standard CPET will be performed without in-line filter

Find a Location

Who is running the clinical trial?

Rush University Medical CenterLead Sponsor
431 Previous Clinical Trials
158,391 Total Patients Enrolled
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterOTHER
104 Previous Clinical Trials
46,573 Total Patients Enrolled
Jie Li, PhDPrincipal InvestigatorRush University Medical Center
9 Previous Clinical Trials
403 Total Patients Enrolled
~2 spots leftby Sep 2025
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