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Broccoli Sulforaphane Bioavailability With Mustard
N/A
Waitlist Available
Research Sponsored by Appalachian State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from pre-ingestion to 8- and 24-hours post-ingestion
Awards & highlights
No Placebo-Only Group
Summary
This trial tests how well healthy adults absorb nutrients from broccoli seed supplements, with or without added mustard seed powder. The study aims to see if mustard seeds help convert a broccoli nutrient into a beneficial compound more effectively. Broccoli and mustard seeds are known for their health benefits, particularly due to compounds like glucoraphanin in broccoli which may reduce cancer and cardiovascular disease risks.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ change from pre-ingestion to 8- and 24-hours post-ingestion
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from pre-ingestion to 8- and 24-hours post-ingestion
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Urine concentration of sulforaphane
Secondary study objectives
Urine concentration of dithiocarbamate
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Broccoli seed extract with mustard seed powderExperimental Treatment1 Intervention
A single dose dietary supplement made up of a mixture of 385 mg broccoli seed extract delivering 50 mg GR (115 umol GR), 145 mg mustard seed powder containing enough active myrosinase (enzyme) to fully hydrolyze the GR in the capsule to SF post-ingestion (\~30 units myrosinase activity) and 100 mg vitamin C (as ascorbic acid).
Group II: Broccoli seed extractActive Control1 Intervention
A single dose dietary supplement made up of 385 mg broccoli seed extract delivering 50 mg GR (115 umol GR) and 100 mg vitamin C (as ascorbic acid).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Broccoli seed extract with mustard seed powder
2022
N/A
~20
Find a Location
Who is running the clinical trial?
Appalachian State UniversityLead Sponsor
44 Previous Clinical Trials
2,504 Total Patients Enrolled
Brassica Foundation for Chemoprotection ResearchUNKNOWN