← Back to Search

Broccoli seed extract with mustard seed powder for Sulforaphane Bioavailability

N/A

Waitlist Available

Research Sponsored by Appalachian State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from pre-ingestion to 8- and 24-hours post-ingestion

Awards & highlights

No Placebo-Only Group

Summary

This trial tests how well healthy adults absorb nutrients from broccoli seed supplements, with or without added mustard seed powder. The study aims to see if mustard seeds help convert a broccoli nutrient into a beneficial compound more effectively. Broccoli and mustard seeds are known for their health benefits, particularly due to compounds like glucoraphanin in broccoli which may reduce cancer and cardiovascular disease risks.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from pre-ingestion to 8- and 24-hours post-ingestion

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from pre-ingestion to 8- and 24-hours post-ingestion

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from pre-ingestion to 8- and 24-hours post-ingestion for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Urine concentration of sulforaphane

Secondary study objectives

Urine concentration of dithiocarbamate

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Broccoli seed extract with mustard seed powderExperimental Treatment1 Intervention

A single dose dietary supplement made up of a mixture of 385 mg broccoli seed extract delivering 50 mg GR (115 umol GR), 145 mg mustard seed powder containing enough active myrosinase (enzyme) to fully hydrolyze the GR in the capsule to SF post-ingestion (\~30 units myrosinase activity) and 100 mg vitamin C (as ascorbic acid).

Group II: Broccoli seed extractActive Control1 Intervention

A single dose dietary supplement made up of 385 mg broccoli seed extract delivering 50 mg GR (115 umol GR) and 100 mg vitamin C (as ascorbic acid).

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Broccoli seed extract with mustard seed powder

2022

N/A

~20

Do I qualify?Apply below to find out