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Nicotine Replacement Therapy

High Strength, Low Strength for Vaping

N/A
Waitlist Available
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 210 minutes
Awards & highlights

Study Summary

This trial will test if e-cigarettes provide efficient nicotine delivery to the brain and arterial blood in smokers and e-cigarette users, and if the liquid characteristics of e-cigarettes modulate this effect.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~210 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 210 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Brain beta-2 nicotinic acetylcholine receptor occupancy
Secondary outcome measures
Maximum arterial blood nicotine

Trial Design

2Treatment groups
Experimental Treatment
Group I: Low Strength, High StrengthExperimental Treatment2 Interventions
Group II: High Strength, Low StrengthExperimental Treatment2 Interventions

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Who is running the clinical trial?

Yale UniversityLead Sponsor
1,863 Previous Clinical Trials
2,742,581 Total Patients Enrolled
2 Trials studying Vaping
295 Patients Enrolled for Vaping
National Institute on Drug Abuse (NIDA)NIH
2,485 Previous Clinical Trials
2,622,380 Total Patients Enrolled
10 Trials studying Vaping
5,072 Patients Enrolled for Vaping
~0 spots leftby Jun 2025
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