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Behavioural Intervention

Hippocampal Stimulation in Chronic Low Back Pain

Chicago, IL
N/A
Waitlist Available
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pain is assessed at baseline, end of first intervention and end of the second intervention.
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing whether TMS can help relieve chronic low back pain by affecting hippocampal network connectivity.

See full description
Eligible Conditions
  • Chronic Pain
  • Back Pain
  • Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 6 weeks - baseline and after the end of hippocampal stimulation
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 6 weeks - baseline and after the end of hippocampal stimulation for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in Pain Scales
Secondary study objectives
Changes in Hippocampal Connectivity

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Sham-stimulationExperimental Treatment1 Intervention
Sham rTMS
Group II: Hippocampus-stimulationExperimental Treatment1 Intervention
Active high-frequency rTMS (20 Hz pulse trains)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation
2017
Completed Phase 4
~730
Sham rTMS
2008
Completed Phase 3
~1020

Find a Location

Closest Location:Northwestern University Feinberg School of Medicine· Chicago, IL

Who is running the clinical trial?

National Institutes of Health (NIH)NIH
2,874 Previous Clinical Trials
8,047,377 Total Patients Enrolled
28 Trials studying Chronic Pain
23,064 Patients Enrolled for Chronic Pain
National Institute on Drug Abuse (NIDA)NIH
2,631 Previous Clinical Trials
3,404,127 Total Patients Enrolled
66 Trials studying Chronic Pain
84,169 Patients Enrolled for Chronic Pain
Northwestern UniversityLead Sponsor
1,664 Previous Clinical Trials
972,748 Total Patients Enrolled
13 Trials studying Chronic Pain
4,092 Patients Enrolled for Chronic Pain
~3 spots leftby Feb 2026