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Behavioral Intervention

Cognitive Therapy vs Exposure Therapy for OCD (RCT_TOC_16 Trial)

N/A

Waitlist Available

Led By Frederick Aardema, Ph. D.

Research Sponsored by Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Primary diagnosis of OCD according to Diagnostical and Statistical Manual, version 5 criteria

Not undergoing a current psychological treatment

Must not have

Another primary diagnosis than OCD requiring treatment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from baseline measure at 6 months

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing a new cognitive therapy approach against exposure and response prevention, the current standard of care, for patients with obsessive-compulsive disorder.

Who is the study for?

This trial is for individuals with Obsessive-Compulsive Disorder (OCD) who are fluent in English or French, have not changed their medication for the past 12 weeks, and do not have a history of substance abuse or certain mental disorders. Participants must be willing to potentially switch treatments and keep medications stable during the study.

What is being tested?

The study compares two OCD treatments: Inference-based cognitive therapy (IBCT), which challenges distorted reasoning without exposure to fears, versus Exposure and Response Prevention (ERP), which involves facing fears directly. The effectiveness, tolerability, and satisfaction rates will be evaluated.

What are the potential side effects?

While specific side effects are not listed for these psychological therapies, participants may experience increased anxiety or distress initially when confronting obsessive thoughts or behaviors during treatment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been diagnosed with OCD based on DSM-5 criteria.

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I am not currently receiving treatment for mental health issues.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am being treated for a condition that is not OCD.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from baseline at 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from baseline at 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline at 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

assess change in level of overvalued ideation

Obsessive-Compulsive Personality

establishing baseline level of overvalued ideation

Other study objectives

assess change in impairment in different domain

Anxiety

assess change in symptoms of depression

+9 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Active Control

Group I: Exposure and response preventionActive Control1 Intervention

ERP is a treatment developed to help people confront their fears based on the rationale that exposure to feared objects, activities, or situations in a safe environment helps reduce fear and decrease avoidance. During the treatment, patients will engage in these exposures to feared stimuli within and between sessions according to hierarchies developed during the initial evaluation sessions, and refrain from engaging in compulsive behaviour until their anxiety subsides (i.e. ritual prevention).

Group II: Inference-based cognitive therapyActive Control1 Intervention

The treatment primarily targets the dysfunctional reasoning and overvalued ideas. IBCT does not include exposure, but aims to bring resolution to the initial obsessional doubt or overvalued idea by showing the participant that the obsession is the result of incorrect reasoning.

0 / 3Eligibility criteria met