Cyclophotocoagulation in Glaucoma

Recruiting in Palo Alto (17 mi)

Overseen by Andrew Toren, Doctor

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: CHU de Quebec-Universite Laval

No Placebo Group

Trial Summary

What is the purpose of this trial?

Transscleral cyclophotocoagulation of the ciliary body is an effective technique to reduce intraocular pressure in case of glaucoma. Due to concerns over complications, the main indications for this second-line treatment are refractory glaucoma medication / surgery and low visual prognosis. The 2000 milliwatts (mW) for 2 seconds settings are used by the majority of researchers and clinicians according to the published literature. Some have proposed using 1250 mW for 4 seconds to improve the use of this medical procedure. The aim of this study is to determine how different parameters affect the efficacy of the treatment. This is a prospective double-blinded randomized controlled trial comparing two groups, the experimental group using 1250 mW for 4 seconds and the control group using 2000 mW for 2 seconds.

Eligibility Criteria

Inclusion Criteria

Patients with poorly controlled high pressure glaucoma

You need a surgical procedure called cyclophotocoagulation to prevent vision loss.

You need a surgery called cyclophotocoagulation to relieve eye pain.

Exclusion Criteria

Patient not able to follow the prescribed post-operative treatment

You have already had treatment for your glaucoma in one eye using cyclophotocoagulation or cryotherapy.

Patients receiving concomitant treatment the same day as the intervention

Treatment Details

Interventions

• Conventional cyclophotocoagulation (Procedure)
• Cyclophotocoagulation protocol (Procedure)
• Modified cyclophotocoagulation (Procedure)

Participant Groups

Group I: Diode laser using modified settings Experimental Treatment 2 Interventions

The cyclophotocoagulation protocol is used with the modified cyclophotocoagulation settings of 1250 mW for 4 seconds.

Group II: Diode laser using conventional settings Active Control 2 Interventions

The cyclophotocoagulation protocol is used with the conventional cyclophotocoagulation settings of 2000 mW for 2 seconds.

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Centre universitaire d'ophtalmologie, Hôpital du Saint-Sacrement. CHU de Québec Québec, Canada

Who Is Running the Clinical Trial?

CHU de Quebec-Universite Laval Lead Sponsor

References