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Somatostatin Analog

Low dose SRL + weekly Pegvisomant for Acromegaly

N/A
Waitlist Available
Led By Shlomo Melmed, MD
Research Sponsored by Cedars-Sinai Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial will compare the effectiveness of two different combinations of drugs to see if a lower dose of one drug can achieve the same results as a higher dose of the same drug.

Eligible Conditions
  • Acromegaly

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Cost Effectiveness

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Active Control
Group I: Low dose SRL + weekly PegvisomantActive Control3 Interventions
Low dose of SRL monthly * Octreotide LAR 10mg * Lanreotide 60mg Weekly Pegvisomant (40-120mg/week)
Group II: High dose SRL + weekly PegvisomantActive Control3 Interventions
High dose of SRL monthly * Octreotide LAR 30mg * Lanreotide 120mg Weekly Pegvisomant (40-120mg/week)
Group III: Low dose SRL + daily PegvisomantActive Control3 Interventions
Low dose of SRL monthly * Octreotide LAR 10mg * Lanreotide 60mg Daily Pegvisomant (15-60mg/day)

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Who is running the clinical trial?

Cedars-Sinai Medical CenterLead Sponsor
512 Previous Clinical Trials
163,288 Total Patients Enrolled
8 Trials studying Acromegaly
287 Patients Enrolled for Acromegaly
Shlomo Melmed, MDPrincipal Investigator - Cedars-Sinai Medical Center
Cedars-Sinai Medical Center, Sound Physicians Platinum Group Pc
University Of Cape Town (Medical School)
7 Previous Clinical Trials
1,475 Total Patients Enrolled
2 Trials studying Acromegaly
163 Patients Enrolled for Acromegaly
~6 spots leftby Nov 2025
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