Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER Trial)

N/A

Waitlist Available

Led By Jessica Brodt, MD

Research Sponsored by Stanford University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up first panel pre-incision; second panel 6hrs (+/-3hrs) post-procedure; third panel 24hrs (+/-3hrs) post-procedure; fourth panel 48hrs (+/-3hrs) post-procedure

Summary

This trial will test if a new pain relief technique can improve outcomes for people undergoing heart surgery.

Eligible Conditions

Acute Pain
Opioid Use Disorder
Local Anesthesia
Cardiovascular Disease

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ first panel pre-incision; second panel 6hrs (+/-3hrs) post-procedure; third panel 24hrs (+/-3hrs) post-procedure; fourth panel 48hrs (+/-3hrs) post-procedure

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~first panel pre-incision; second panel 6hrs (+/-3hrs) post-procedure; third panel 24hrs (+/-3hrs) post-procedure; fourth panel 48hrs (+/-3hrs) post-procedure

This trial's timeline: 3 weeks for screening, Varies for treatment, and first panel pre-incision; second panel 6hrs (+/-3hrs) post-procedure; third panel 24hrs (+/-3hrs) post-procedure; fourth panel 48hrs (+/-3hrs) post-procedure for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Opioid Consumption

Secondary study objectives

Delirium and agitation post-operatively

Determine post-operative pain scores

Inflammatory biomarker analysis

+4 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Bilateral ESP catheter with LidocaineExperimental Treatment1 Intervention

All participants will get the Erector Spinae Plane (ESP) catheters. Prior to transfer to the operating room, participants will receive bilateral ESP catheters at T7 level under ultrasound guidance. This arm is the treatment group and will receive lidocaine via alternating side automated infusion pump bolus dosing, continued until chest tube removal or postoperative day 5 (whichever occurs earliest).

Group II: Bilateral ESP catheter with salinePlacebo Group1 Intervention

All participants will get the Erector Spinae Plane (ESP) catheters. This arm is the control group and will have normal saline administered via ESP catheters, continued until chest tube removal or postoperative day 5 (whichever occurs earliest).

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