A Prospective Clinical Study of Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Ⅱ AEG

Recruiting in Palo Alto (17 mi)

Overseen bywei wang, M.D.,Ph.D

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Guangdong Provincial Hospital of Traditional Chinese Medicine

No Placebo Group

Trial Summary

What is the purpose of this trial?

Objective: To evaluate the safety, feasibility and clinical efficacy of transthoracic single-hole assisted laparoscopic radical gastrectomy for Siewert Type Ⅱ adenocarcinoma of esophagogastric junction. Methods: A prospective, single-center, one-arm study will be performed. Patients who have been diagnosed with Siewert type Ⅱ esophagogastric junction adenocarcinoma and meet the eligibility criteria will be included in the study and undergo the transthoracic single-hole assisted laparoscopic radical gastrectomy. The data of preoperative, intraoperative, postoperative and follow-up will be recorded and analyzed. Primary study endpoints: The incidences of early postoperative complications and mortality. The secondary study endpoints:(1) Surgery and oncology indicators ;(2) Early postoperative recovery information ;(3) 3-year disease-free survival and overall survival rate;(4) 5-year disease-free survival and overall survival.

Research Team

wei wang, M.D.,Ph.D

Principal Investigator

Guangdong PHTCM

Eligibility Criteria

Inclusion Criteria

Informed consent of patients;

The tumor invaded the anatomy esophagogastric junction (EGJ), with the tumor center located at the EGJ line from 1cm above to 2cm below(SiewertⅡ).

The endoscopic biopsy was diagnosed with adenocarcinoma;

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Treatment Details

Interventions

Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy (Procedure)

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Research groupExperimental Treatment1 Intervention

Patients diagnosed with Siewert Ⅱ adenocarcinoma of esophagogastric junction and met the inclusion criteria will be assigned to the research group and carry out transthoracic single-hole assisted laparoscopic radical gastrectomy.