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Behavioural Intervention

The Effect of Rapid Transcranial Magnetic Stimulation (rTMS) on Aggression in Forensic Patients

N/A
Waitlist Available
Led By Gary Chaimowitz, MD, FRCPC
Research Sponsored by St. Joseph's Healthcare Hamilton
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 days
Awards & highlights
No Placebo-Only Group

Summary

Forensic patients will undergo 30 rTMS treatments, once per day each business day using a 1Hz frequency at the right dorso-lateral pre frontal cortex, located using modified BEAM F3. Patients will be assessed before and after the study with a battery of assessments and using 2 computer tasks: a ball passing task, and the Point Subtraction Aggression Paradigm (PSAP). The investigators will also monitor and record aggressive incidents that take place on the unit.

Eligible Conditions
  • Aggression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in Aggressive Incident Scale (AIS)
Other study objectives
Change in Ball sharing task score
Change in Point Subtraction Aggression Paradigm (PSAP)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: rTMSExperimental Treatment1 Intervention
treatment with repetitive transcranial magnetic stimulation for 30 days
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
rTMS
2016
Completed Phase 3
~840

Find a Location

Who is running the clinical trial?

St. Joseph's Healthcare HamiltonLead Sponsor
202 Previous Clinical Trials
26,915 Total Patients Enrolled
1 Trials studying Aggression
50 Patients Enrolled for Aggression
University Health Network, TorontoOTHER
1,531 Previous Clinical Trials
504,312 Total Patients Enrolled
2 Trials studying Aggression
130 Patients Enrolled for Aggression
Gary Chaimowitz, MD, FRCPCPrincipal InvestigatorHead of Forensics
1 Previous Clinical Trials
20 Total Patients Enrolled
~1 spots leftby Dec 2025
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