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Behavioural Intervention

Repetitive transcranial magnetic stimulation (rTMS) for Alcoholism

N/A
Waitlist Available
Led By Jon M Houck, PhD
Research Sponsored by The Mind Research Network
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks

Summary

This trial is testing a brain stimulation technique called rTMS on adults with Alcohol Use Disorder. The goal is to see if it can reduce cravings and negative emotions by using magnetic pulses to change brain activity. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique that has been explored for treating various substance use disorders, including alcohol use disorder.

Eligible Conditions
  • Alcoholism

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in cerebellar brain activation as indicated by percent signal change in the medial cerebellum during incongruent minus congruent trials during a multisensory Stroop task during fMRI
Change in percent days abstinent as measured by the Time Line Follow Back
Change in self reported negative affect as measured by the Promise anger, anxiety and depression scales
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Cerebellar rTMSExperimental Treatment1 Intervention
Cerebellar rTMS. 1Hz repetitive transcranial magnetic stimulation (rTMS) to cerebellar vermis.
Group II: Sham TMSPlacebo Group1 Intervention
Sham TMS. Sham transcranial magnetic stimulation to cerebellar vermis.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Repetitive transcranial magnetic stimulation (rTMS)
2021
Completed Phase 4
~730

Find a Location

Who is running the clinical trial?

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
835 Previous Clinical Trials
1,082,746 Total Patients Enrolled
456 Trials studying Alcoholism
823,762 Patients Enrolled for Alcoholism
The Mind Research NetworkLead Sponsor
26 Previous Clinical Trials
2,318 Total Patients Enrolled
8 Trials studying Alcoholism
1,012 Patients Enrolled for Alcoholism
Jon M Houck, PhDPrincipal InvestigatorThe Mind Research Network
~4 spots leftby Nov 2025
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