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Behavioural Intervention
Transcranial Magnetic Stimulation (TMS) Treatment for Alcohol Use Disorder
N/A
Waitlist Available
Led By Nassima Ait-Daoud TIouririne, M.D.
Research Sponsored by Nassima Ait-Daoud Tiouririne
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 months
Summary
This is a pilot study designed to evaluate the efficacy of High Frequency (HF) repetitive transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex (L-DLPFC) at improving cognitive flexibility in recently detoxified individuals with alcohol use disorder (AUD) compared to placebo (Sham rTMS). The total number of subjects requested to be randomized is 20. The investigator will need to screen about 40 subjects to have 20 subjects started on rTMS session at a ratio of 2 screens/1 subject randomized.
Eligible Conditions
- Alcohol Use Disorder
- Alcoholism
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 months
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Dimensional Change Card Sort Task (DCCST)
Flanker Inhibitory Control and Attention Test (FICAT)
List Sorting Working Memory Test (LSWMT)
+1 moreSecondary study objectives
Alcohol Craving Questionnaire (ACQ-NOW)
Drinks Per Drinking Day
Percentage of Days of Abstinence
+1 moreTrial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Transcranial Magnetic Stimulation (rTMS)Experimental Treatment1 Intervention
repetitive transcranial magnetic stimulation
Group II: Sham (SS)Placebo Group1 Intervention
repetitive sham rTMS
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation (rTMS)
2011
N/A
~100
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Who is running the clinical trial?
Nassima Ait-Daoud TiouririneLead Sponsor
2 Previous Clinical Trials
216 Total Patients Enrolled
Nassima Ait-Daoud TIouririne, M.D.Principal InvestigatorUniversity of Virginia