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Behavioural Intervention

Transcranial Magnetic Stimulation (TMS) Treatment for Alcohol Use Disorder

N/A
Waitlist Available
Led By Nassima Ait-Daoud TIouririne, M.D.
Research Sponsored by Nassima Ait-Daoud Tiouririne
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 months

Summary

This is a pilot study designed to evaluate the efficacy of High Frequency (HF) repetitive transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex (L-DLPFC) at improving cognitive flexibility in recently detoxified individuals with alcohol use disorder (AUD) compared to placebo (Sham rTMS). The total number of subjects requested to be randomized is 20. The investigator will need to screen about 40 subjects to have 20 subjects started on rTMS session at a ratio of 2 screens/1 subject randomized.

Eligible Conditions
  • Alcohol Use Disorder
  • Alcoholism

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Dimensional Change Card Sort Task (DCCST)
Flanker Inhibitory Control and Attention Test (FICAT)
List Sorting Working Memory Test (LSWMT)
+1 more
Secondary study objectives
Alcohol Craving Questionnaire (ACQ-NOW)
Drinks Per Drinking Day
Percentage of Days of Abstinence
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Transcranial Magnetic Stimulation (rTMS)Experimental Treatment1 Intervention
repetitive transcranial magnetic stimulation
Group II: Sham (SS)Placebo Group1 Intervention
repetitive sham rTMS
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation (rTMS)
2011
N/A
~100

Find a Location

Who is running the clinical trial?

Nassima Ait-Daoud TiouririneLead Sponsor
2 Previous Clinical Trials
216 Total Patients Enrolled
Nassima Ait-Daoud TIouririne, M.D.Principal InvestigatorUniversity of Virginia
~3 spots leftby Dec 2025