Virtual Music Therapy for Alzheimer's Disease

N/A

Recruiting

Led By Alexander Pantelyat, MD

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 18-89

Mild Cognitive Impairment (MoCA score: 18-25) or Early AD (MoCA score: 17-24)

Must not have

Head trauma, traumatic brain injury, or concussion with loss of consciousness for >2 minutes

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 1, day 3, day 8, day 10, day 15, day 17, day 22, day 24, day 29, day 31, day 36, day 38, day 43, day 45, day 50, day 52

Awards & highlights

No Placebo-Only Group

Summary

This trial will assess if reminiscence-based virtual music therapy can help people with MCI or mild dementia due to AD by enhancing their autobiographical memory, mood, and cognition.

Who is the study for?

This trial is for adults aged 18-89 with mild cognitive impairment or early Alzheimer's Disease, as indicated by specific scores on a cognitive assessment test (MoCA). It excludes those who've had significant head trauma, are claustrophobic to the extent that they can't undergo MRI scans, have medical devices or metal in their body that interfere with MRI technology.

What is being tested?

The study tests if virtual music therapy sessions focused on reminiscence can improve memory, mood, and thinking abilities in patients. Participants will attend two sessions per week over eight weeks. Their self-reported feelings and objective measures of cognition will be evaluated before and after treatment using fMRI imaging.

What are the potential side effects?

Since this trial involves non-invasive music therapy, there are no direct physical side effects expected from the intervention itself. However, participants may experience varying emotional responses to the therapy.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 18 and 89 years old.

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My memory test score indicates mild cognitive issues or early Alzheimer's.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have had a head injury with unconsciousness for more than 2 minutes.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 1, day 3, day 8, day 10, day 15, day 17, day 22, day 24, day 29, day 31, day 36, day 38, day 43, day 45, day 50, day 52

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 1, day 3, day 8, day 10, day 15, day 17, day 22, day 24, day 29, day 31, day 36, day 38, day 43, day 45, day 50, day 52

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1, day 3, day 8, day 10, day 15, day 17, day 22, day 24, day 29, day 31, day 36, day 38, day 43, day 45, day 50, day 52 for reporting.