Imaging Study for ALS
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to better understand ALS, a progressive nerve disease, by identifying biomarkers that indicate disease progression over time. Participants will undergo brain and spine MRIs and have blood tests up to four times a year. The trial includes two groups: one with early-stage ALS and another with healthy individuals for comparison. Those who have experienced ALS symptoms for less than three years and can safely undergo an MRI may be suitable candidates. As an unphased study, this trial offers participants the chance to contribute to groundbreaking research that could enhance the understanding and treatment of ALS.
Why are researchers excited about this trial?
Researchers are excited about the Multicenter ALS Imaging Study because it aims to uncover new insights into early-stage ALS using advanced imaging techniques. Unlike traditional treatments that focus on slowing disease progression, this study seeks to enhance our understanding of ALS by comparing brain images of participants with and without the disease. By identifying specific brain changes in ALS patients, researchers hope to pave the way for earlier diagnosis and more targeted therapies in the future. This approach is unique because it shifts the focus from treatment to understanding the underlying mechanisms of ALS, potentially transforming how we approach this challenging condition.
Who Is on the Research Team?
Pramod Pisharady, PhD
Principal Investigator
University of Minnesota
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo initial MRI scans, blood tests, and neurological exams
Longitudinal Assessment
Participants undergo MRI scans, blood tests, and neurological exams at 3, 6, and 12 months
Follow-up
Participants are monitored for safety and effectiveness after the main assessments
What Are the Treatments Tested in This Trial?
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Control participants free from neurological disease
Adults with early stage ALS
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Minnesota
Lead Sponsor
Food and Drug Administration (FDA)
Collaborator
Minnesota Office of Higher Education
Collaborator
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