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Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
healthy adults 18 and 35
healthy adults 18 to 55
Must not have
current and regular use of prescription medications related to mental health disorders
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 hours following the completion of fear extinction procedures
Awards & highlights
No Placebo-Only Group
Summary
This trial will study whether social support reminders can help reduce fear in people with anxiety disorders.
Who is the study for?
This study is for adults aged 18-55, with or without social anxiety disorder. Healthy participants must have no mental illness history, while anxious ones can also have depression or PTSD but not bipolar, psychosis, substance use disorders. Participants should speak English fluently and not be on mental health meds or pregnant.
What is being tested?
Researchers at UCLA are testing if reminders of a social support figure can help reduce fear in people with anxiety disorders as it does in healthy individuals. The test involves pairing images of either a support figure or stranger with threatening cues without actual shock to see if this reduces fear over time.
What are the potential side effects?
Since the intervention involves psychological procedures rather than medications, traditional side effects like those seen with drugs are not expected. However, participants may experience stress or discomfort during the fear extinction tasks.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 35 years old.
Select...
I am a healthy adult between 18 and 55 years old.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I regularly take prescription medication for a mental health disorder.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ within experimental session - directly post-extinction procedure
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~within experimental session - directly post-extinction procedure
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Fear response 24 hours post-extinction
Fear response directly post-extinction
Side effects data
From 2020 Phase 2 trial • 49 Patients • NCT0331617029%
Insomnia
25%
Breathing difficulty
25%
Dry mouth
21%
Dizziness
17%
Weakness
17%
Sore throat
17%
Headache
17%
Heartburn
13%
Burning in throat or mouth
13%
Diarrhea
8%
Irregular heartbeat
8%
Rapid heartbeat
8%
Skin irritation
8%
Skin itchiness
8%
Skin redness
8%
Sore mouth
4%
Skin swelling
4%
Vomiting or nausea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Social Support + NRT Sampling
Social Support
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: Social SupportExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Social Support
2022
Completed Phase 2
~3490
Find a Location
Who is running the clinical trial?
University of California, Los AngelesLead Sponsor
1,565 Previous Clinical Trials
10,263,089 Total Patients Enrolled
35 Trials studying Anxiety
38,357 Patients Enrolled for Anxiety
National Institute of Mental Health (NIMH)NIH
2,918 Previous Clinical Trials
2,740,072 Total Patients Enrolled
91 Trials studying Anxiety
41,894 Patients Enrolled for Anxiety
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I am between 18 and 35 years old.You have been diagnosed in the past with a mental illness such as anxiety, depression, or phobias, and/or have been prescribed medication for a mental health disorder.I am a healthy adult between 18 and 55 years old.I have been diagnosed with social anxiety disorder and may also have depression, other anxiety disorders, or PTSD.I regularly take prescription medication for a mental health disorder.You have certain mental health conditions such as bipolar disorder, psychosis, substance use disorder, neurological disorder, and/or obsessive-compulsive disorder that are not allowed in this study.You have never been diagnosed with a mental illness by a mental health professional, including anxiety, depression, phobia, or any other related disorder.
Research Study Groups:
This trial has the following groups:- Group 1: Social Support
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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