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Behavioral Intervention

Speech Treatment for Minimally Verbal Children with Autism (TxMVASD+CAS Trial)

N/A
Recruiting
Research Sponsored by MGH Institute of Health Professions
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Meets criteria for Childhood Apraxia of Speech
Able to correctly repeat at least 2 syllables
Must not have
Poorly controlled seizures
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial tests if adding CAS-specific therapy to minimally verbal children with autism will improve their speech development.

Who is the study for?
This trial is for minimally verbal children with Autism Spectrum Disorder who can repeat at least 2 syllables and meet the criteria for Childhood Apraxia of Speech. They should not speak more than 20 words or phrases and must be exposed to English at least half the time. Children with poorly controlled seizures, sensory disabilities, or severe behavioral issues cannot participate.
What is being tested?
The study tests a speech treatment designed specifically for children with both autism and CAS (a speech movement planning disorder). It aims to see if this tailored therapy helps improve their ability to speak.
What are the potential side effects?
Since this is a speech therapy intervention, traditional medication side effects are not expected. However, there may be fatigue or frustration during treatment sessions due to the challenges associated with learning new speech skills.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been diagnosed with Childhood Apraxia of Speech.
Select...
I can repeat at least two syllables correctly.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
My seizures are not well-controlled.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Attempts Correct
Phonemes Correct
Secondary study objectives
Lip aperture movement variability
Phoneme distinctiveness

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: CAS Treatment for MV ASDExperimental Treatment1 Intervention
Participants will receive CAS treatment, modified for minimally verbal children with autism

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Who is running the clinical trial?

MGH Institute of Health ProfessionsLead Sponsor
16 Previous Clinical Trials
2,021 Total Patients Enrolled
~13 spots leftby Dec 2025
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