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3D MRI Technique for Rheumatoid Arthritis

N/A
Recruiting
Led By Naveen Murthy, MD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Hand radiographs confirm the presence of bony erosions
Be older than 18 years old
Must not have
Less than 18 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 day
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to study a new MRI technique called 3D DL oZTEo to detect bone erosion in the hands of patients with inflammatory arthritis. Detecting bone changes is important in diseases like

Who is the study for?
This trial is for patients with inflammatory arthritis, such as rheumatoid arthritis, who need their hand bones checked for damage. The study will use a new MRI technique to spot bone erosion.
What is being tested?
The trial is testing a new MRI pulse sequence called 3D DL oZTEo. It's designed to better detect bone erosions in the hands of patients with inflammatory arthritis compared to current methods.
What are the potential side effects?
Since this trial involves an imaging technique rather than a drug or invasive procedure, there are no direct side effects expected from the intervention itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My X-rays show bone damage in my hands.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am under 18 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 day
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
The binary (yes/no) presence of bony erosions as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.
Secondary study objectives
The number of erosions (continuous) as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: oZTEo MRI pulse sequenceExperimental Treatment1 Intervention
All patients will have the FDA approved MRI pulse sequence, oZTEo, added to their already ordered standard of care MRI examination.

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,360 Previous Clinical Trials
3,065,916 Total Patients Enrolled
6 Trials studying Rheumatoid Arthritis
571 Patients Enrolled for Rheumatoid Arthritis
GE HealthcareIndustry Sponsor
303 Previous Clinical Trials
633,930 Total Patients Enrolled
Naveen Murthy, MDPrincipal InvestigatorMayo Clinic
~17 spots leftby Jun 2026
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