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Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm

N/A
Waitlist Available
Led By David A. Kaminsky, MD
Research Sponsored by University of Vermont
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play an important role. The investigators will be measuring these chemicals in the exhaled breath of volunteers with exercise induced asthma as they undergo a test to mimic exercise induced asthma. The investigators will determine how the levels of these chemicals change in association with how lung function changes before, during and after an episode of exercise induced asthma.

Eligible Conditions
  • Exercise-Induced Asthma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: AsthmaticsExperimental Treatment1 Intervention
Asthmatics with exercise induced bronchospasm
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Hyperpnea challenge
2007
N/A
~10

Find a Location

Who is running the clinical trial?

University of VermontLead Sponsor
278 Previous Clinical Trials
3,744,136 Total Patients Enrolled
David A. Kaminsky, MDPrincipal InvestigatorUniversity of Vermont
~0 spots leftby Dec 2025