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Behavioural Intervention

EEG Biomarkers for Chronic Lower Back Pain

N/A
Recruiting
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 1-month, 2-month and 5-month follow-ups
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to study chronic low back pain (CLBP) by using brain-based biomarkers to predict symptom progression. The researchers will use electroencephalogram (EEG) neuroimaging

Who is the study for?
This trial is for adults with chronic low back pain (CLBP) who can speak English. It's not suitable for individuals with cancer, severe psychiatric conditions, those involved in injury litigation or receiving workers' compensation benefits.
What is being tested?
The study tests if EEG-based biomarkers can predict the progression of CLBP symptoms. Participants will undergo EEGs to track brain activity related to resting state, emotions, and cognition at baseline and then after 3 and 6 months.
What are the potential side effects?
There are no direct side effects from participating in this trial as it involves non-invasive EEG testing. However, some participants might experience discomfort from wearing the EEG cap or sitting still during the procedure.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 1-month, 2-month and 5-month follow-ups
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1-month, 2-month and 5-month follow-ups for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
EEG error related negativity changes from baseline
EEG late positive potential changes from baseline
EEG resting state functional connectivity changes from baseline
+1 more
Secondary study objectives
Neuropsychological changes from baseline as assessed by the NIH toolbox

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Single ArmExperimental Treatment3 Interventions
All participants will complete all interventions

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Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,491 Previous Clinical Trials
17,519,082 Total Patients Enrolled
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NIH
502 Previous Clinical Trials
1,089,888 Total Patients Enrolled
~68 spots leftby Feb 2026
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