Tethered Capsule Endomicroscopy for Barrett's Esophagus

Recruiting in Palo Alto (17 mi)

Overseen byGuillermo Tearney, M.D, PhD.

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Massachusetts General Hospital

No Placebo Group

Trial Summary

What is the purpose of this trial?The investigators will conduct a large study in the primary care clinic to determine the feasibility of using tethered capsule endomicroscopy as a screening method for Barrett's esophagus (BE) in the primary care practice environment. The investigators are also determining the prevalence of Barrett's esophagus in a primary care practice cohort at MGH.

Eligibility Criteria

This trial is for adults aged 18-75 who are patients at the Assembly Row primary care practice, can consent to participate, and haven't eaten for an hour before the procedure. It's not for pregnant individuals, those with swallowing difficulties, urgent symptoms like fever or abdominal pain, a history of certain GI surgeries or Crohn's disease.

Inclusion Criteria

I am 18 years old or older.

Subjects registered as patients at the Assembly Row primary care practice.

Able to give informed consent

+1 more

Exclusion Criteria

I am currently having difficulty swallowing.

I have a narrow GI passage, had GI surgery, or have Crohn's disease.

I am scheduled for an urgent care visit due to symptoms like fever or abdominal pain.

+2 more

Participant Groups

The study is testing tethered capsule endomicroscopy as a way to screen for Barrett's Esophagus in a regular doctor’s office setting. The goal is to see if this method works well in primary care and how common Barrett's Esophagus is among these patients.

1Treatment groups

Experimental Treatment

Group I: Feasibility of TCE & Prevalence of BEExperimental Treatment1 Intervention

1. Feasibility of using tethered capsule endomicroscopy as a screening method for Barrett's esophagus in the primary care practice environment 2. Determine the prevalence of Barrett's esophagus in a primary care practice cohort at MGH