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Mindfulness-Based Weight Loss Therapy for Obesity (Activate Trial)

N/A

Waitlist Available

Led By Evan M Forman, PhD

Research Sponsored by Drexel University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Inability to engage in physical activity (defined as walking a city block without stopping)

History of bariatric surgery; weight loss of > 5% in the previous 3 months

Timeline

Screening 3 weeks

Treatment Varies

Follow Up measured at baseline, mid-treatment (6 months), post-treatment (12 months), and at 6-, 12-, and 24-month follow-up (i.e., at 0, 6, 12, 18, 24 and 36 months).

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether adding three components of mindfulness and acceptance based behavioral therapy (MABT) to remotely delivered weight loss counseling helps people lose weight, and identify which subsets of people are most responsive to each component.

Who is the study for?

Adults aged 18-70 with a BMI of 27-50 kg/m2 who are willing to lose weight, be physically active, and attend group sessions can join. They must complete food diaries and baseline tasks, and allow the team to consult their doctor if needed. Those unable to exercise, pregnant or breastfeeding women, people planning other weight loss treatments or changes in medications that affect weight cannot participate.

What is being tested?

The trial is testing three core components of Mindfulness and Acceptance based Behavioral Therapies (MABTs) for obesity: Awareness, Acceptance, Values Clarity. These will be added to remote counseling for weight loss using a factorial design to see which parts work best alone or together.

What are the potential side effects?

Since this trial involves behavioral therapy rather than medication, there aren't typical side effects like you'd expect from drugs. Participants may experience emotional discomfort as they confront personal habits related to eating and lifestyle.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I cannot walk a city block without stopping.

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I have had weight loss surgery and lost more than 5% of my weight in the last 3 months.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ measured at baseline, mid-treatment (6 months), post-treatment (12 months), and at 6-, 12-, and 24-month follow-up (i.e., at 0, 6, 12, 18, 24 and 36 months).

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~measured at baseline, mid-treatment (6 months), post-treatment (12 months), and at 6-, 12-, and 24-month follow-up (i.e., at 0, 6, 12, 18, 24 and 36 months).

This trial's timeline: 3 weeks for screening, Varies for treatment, and measured at baseline, mid-treatment (6 months), post-treatment (12 months), and at 6-, 12-, and 24-month follow-up (i.e., at 0, 6, 12, 18, 24 and 36 months). for reporting.