Hyperbaric Oxygen Therapy for Concussion

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Male

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Michael Harl

No Placebo Group

Trial Summary

What is the purpose of this trial?

The use of Hyberbaric Oxygen Therapy (HBOT) would be a new treatment plan rather than conventional rest. If effective, this new use technology would add to the clinical treatment among mild traumatic brain injury (mTBI) patients. The use of a point of care Glial Fibrillary Acidic Protein (GFAP) biomarker would aid in clinical decision making to create a new care plan of return to sport among unarmed combat athletes who suffer from mTBI. The innovation would be a new treatment and diagnosis strategy that will protect these athletes from serious long-term sequelae. There are no published randomized controlled studies using HBOT to treat concussed athletes within one week of injury. There are no published studies using GFAP levels to predict post concussive symptoms (PCS).

Research Team

Eligibility Criteria

This trial is for unarmed combat athletes who have recently experienced a mild traumatic brain injury (mTBI), such as a concussion, and are dealing with symptoms like headaches. They should not have had any serious injuries at home or other types of brain injuries.

Inclusion Criteria

I have a head injury with a specific suspension time due to the injury's severity.

Exclusion Criteria

I will be randomly assigned to receive either hyperbaric oxygen therapy or standard rest care.

Treatment Details

Interventions

Hyberbaric Oxygen Therapy (Oxygen Therapy)

Trial OverviewThe study is testing Hyperbaric Oxygen Therapy (HBOT) as an alternative to the usual rest treatment for mTBI. It also examines using Glial Fibrillary Acidic Protein (GFAP) levels to decide when athletes can return to sport safely.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: HBOT Treatment GroupExperimental Treatment1 Intervention

Group II: Conventional Rest Control GroupActive Control1 Intervention