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CT Perfusion Imaging for Subarachnoid Hemorrhage (CT-PIPS Trial)
N/A
Waitlist Available
Led By Gwynedd E Pickett, MD
Research Sponsored by Nova Scotia Health Authority
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline
Awards & highlights
No Placebo-Only Group
Summary
This trialwill test if CT scans can predict which SAH patients are at risk of stroke from vasospasm, helping to improve their outcomes.
Who is the study for?
This trial is for individuals aged 18-75 who have had a brain hemorrhage due to a ruptured aneurysm and can consent to participate. They must be able to attend follow-up visits and not be in another study, pregnant, breastfeeding, or expected to pass away within 24 hours.
What is being tested?
The trial tests if CT perfusion scans can predict vasospasm—a dangerous narrowing of blood vessels in the brain after hemorrhage—by performing scans when patients are admitted and again on day six.
What are the potential side effects?
CT perfusion involves exposure to radiation similar to that of regular CT scans. Potential side effects include allergic reactions to contrast material used during the scan, such as itching or rash.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
CBF Admit
CBF day 6
CBV Admit
+5 moreSecondary study objectives
Radiation Dose
Other study objectives
Delayed Cerebral Ischemia
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: CT PerfusionExperimental Treatment1 Intervention
All patients enrolled in the study
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
CT Perfusion
2013
N/A
~340
Find a Location
Who is running the clinical trial?
Nova Scotia Health AuthorityLead Sponsor
287 Previous Clinical Trials
94,281 Total Patients Enrolled
Gwynedd PickettLead Sponsor
Gwynedd E Pickett, MDPrincipal InvestigatorCapital District Health Authority, Halifax, Canada
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You are younger than 18 or older than 75 years old.The patient is not expected to live for more than 24 hours, for example, if they have lost certain reflexes or are being considered for organ donation instead of treatment.You are between 18 and 75 years old.You have a documented brain aneurysm that has ruptured.
Research Study Groups:
This trial has the following groups:- Group 1: CT Perfusion
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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