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Behavioural Intervention

Cognitive Training for Brain Cancer

N/A
Recruiting
Led By Andrew Heitzer, PhD, ABPP-CN
Research Sponsored by St. Jude Children's Research Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after approach for enrollment, an average of 3 weeks after starting radiation therapy
Awards & highlights
No Placebo-Only Group

Summary

This trial investigates feasibility & acceptability of cognitive training via virtual reality & iPad for children with brain tumors undergoing radiotherapy to improve quality of life. Results will inform a larger trial.

Who is the study for?
This trial is for children aged 8-22 undergoing radiotherapy for brain tumors, who speak English or Spanish. They and a parent must agree to participate and follow the study's procedures. It excludes those with an IQ < 70, severe psychiatric conditions, major sensory/motor impairments that affect testing, significant neurological history before their tumor diagnosis, or need for general anesthesia during treatment.
What is being tested?
The study tests cognitive training using either an iPad or virtual reality (VR) to see if VR is feasible and acceptable in this setting. Children will be randomly assigned to one of these methods and undergo cognitive tests plus brain activity exams before and after the intervention to assess potential neurocognitive benefits.
What are the potential side effects?
While not explicitly mentioned, side effects may include discomfort from wearing VR equipment, eye strain from screen use on both iPad and VR devices, possible motion sickness from VR use, and fatigue due to concentration required during cognitive training sessions.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after approach for enrollment, an average of 3 weeks after starting radiation therapy
This trial's timeline: 3 weeks for screening, Varies for treatment, and after approach for enrollment, an average of 3 weeks after starting radiation therapy for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Adherence
Participation Rate
Side Effects
Secondary study objectives
Cerebral Hemodynamics
Neurobehavioral

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Virtual Reality Cogmed TrainingExperimental Treatment1 Intervention
The investigator will be randomizing participants to complete Cogmed training in Virtual Reality.
Group II: IPad Cogmed TrainingActive Control1 Intervention
The investigator will be randomizing participants to complete Cogmed training on an iPad.

Find a Location

Who is running the clinical trial?

St. Jude Children's Research HospitalLead Sponsor
443 Previous Clinical Trials
5,305,406 Total Patients Enrolled
Andrew Heitzer, PhD, ABPP-CNPrincipal InvestigatorSt. Jude Children's Research Hospital
Heather Conklin, PhDPrincipal InvestigatorSt. Jude Children's Research Hospital
2 Previous Clinical Trials
144 Total Patients Enrolled

Media Library

Cognitive training via iPad (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05947045 — N/A
Brain Tumor Research Study Groups: IPad Cogmed Training, Virtual Reality Cogmed Training
Brain Tumor Clinical Trial 2023: Cognitive training via iPad Highlights & Side Effects. Trial Name: NCT05947045 — N/A
Cognitive training via iPad (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05947045 — N/A
~4 spots leftby Mar 2025