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Acute Exercise for Breast Cancer (WISER-WIN Trial)

N/A
Waitlist Available
Led By Kathleen Sturgeon, PhD, MEd, MS
Research Sponsored by Milton S. Hershey Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet
Awards & highlights

WISER-WIN Trial Summary

This trial is looking at how physical activity affects breast cancer patients by looking at changes in the tumor, how much oxygen it gets, and the levels of circulating tumor DNA and exerkines.

WISER-WIN Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in deoxy-hemoglobin
Changes in oxy-hemoglobin
Changes in oxygen saturation
+1 more
Secondary outcome measures
Changes in ctDNA level
Exerkine: S1P
Exerkine: TGF-β
+2 more

WISER-WIN Trial Design

1Treatment groups
Experimental Treatment
Group I: Acute exerciseExperimental Treatment1 Intervention
Participants will be asked to walk or jog on a treadmill for a maximal exercise test.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acute Exercise
2022
Completed Phase 3
~30

Find a Location

Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor
497 Previous Clinical Trials
2,799,967 Total Patients Enrolled
14 Trials studying Breast Cancer
634 Patients Enrolled for Breast Cancer
Kathleen Sturgeon, PhD, MEd, MSPrincipal InvestigatorPenn state University College of Medicine
~1 spots leftby Jun 2025
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