Exercise, Fitness and Tumor Profiling in Breast Cancer Patients

Recruiting in Palo Alto (17 mi)

+9 other locations

Overseen byLee Jones, MD, PhD

Age: 18+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Memorial Sloan Kettering Cancer Center

No Placebo Group

Approved in 1 Jurisdiction

Trial Summary

What is the purpose of this trial?

This study is designed to find out how engaging in regular exercise (or not) alters the biology of breast tumors as well as the normal tissue (if available) surrounding the tumor. The investigators hope that findings from this initial study will guide the design of future studies to examine how changes in exercise alter breast tumor biology.

Research Team

Lee Jones, MD, PhD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Eligibility Criteria

Inclusion Criteria

Stage I to II disease

Scheduled for surgical resection by any type of mastectomy or lumpectomy at MSK

Tumor size ≥1cm by preoperative imaging or physical examination

See 7 more

Treatment Details

Interventions

Exercise (Behavioral Intervention)

Participant Groups

2Treatment groups

Experimental Treatment

Group I: Regular exercisers who are at high risk of developing breast cancerExperimental Treatment2 Interventions

≥120 minutes of vigorous-intensity aerobic exercise;

Group II: Regular exercisers and non-exercising groups who have been diagnosed with breast cancerExperimental Treatment5 Interventions

There is no treatment on this study, it is a onetime assessment. exercisers: ≥120 minutes of vigorous-intensity aerobic exercise;There is no treatment on this study, it is a onetime assessment. non-exercisers: ≤ 30 minutes of moderate-intensity exercise per week.