~2 spots leftby Mar 2026

Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor

Recruiting in Palo Alto (17 mi)
Overseen BySumanta Pal
Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: City of Hope Medical Center
No Placebo Group

Trial Summary

What is the purpose of this trial?This randomized clinical trial studies how well probiotic yogurt supplement works in reducing diarrhea in patients with kidney cancer that has spread from the primary site to other places in the body (metastatic) and that are being treated with vascular endothelial growth factor-tyrosine kinase inhibitor therapy. Studying samples of blood and stool from patients who eat probiotic yogurt and those who avoid probiotic yogurt may help doctors plan better treatment.

Eligibility Criteria

Participant Groups

2Treatment groups
Experimental Treatment
Active Control
Group I: Arm I (probiotic yogurt supplement)Experimental Treatment3 Interventions
Patients receive probiotic supplement Activia yogurt QD during weeks 2-13 of VEGF-TKI treatment.
Group II: Arm II (no intervention)Active Control2 Interventions
Patients avoid any intake of yogurt or yogurt-containing foods and refrain from taking/consuming other probiotic supplements for 3 months.

Find A Clinic Near You

Research locations nearbySelect from list below to view details:
City of Hope Medical CenterDuarte, CA
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Who is running the clinical trial?

City of Hope Medical CenterLead Sponsor
National Cancer Institute (NCI)Collaborator

References