Dietary Inflammatory Potential for Breast Cancer Risk
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines how diet might influence the risk of developing breast cancer. Researchers aim to determine if certain foods could increase or decrease this risk, potentially aiding in the development of improved prevention strategies. Participants will undergo regular check-ups and complete questionnaires over several years to collect this data. The trial includes a dietary intervention, also known as nutritional counseling or dietary therapy, and suits individuals at high risk for breast cancer due to family history or specific medical conditions like atypical breast changes.
As an unphased trial, it provides participants the chance to contribute to groundbreaking research that could lead to new prevention strategies.
Do I have to stop taking my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this dietary intervention is safe?
Research shows that dietary changes can affect breast cancer risk and enhance quality of life. Studies have found that certain eating habits might reduce the chance of cancer recurrence and support overall health. Evidence also suggests that these diets can aid during cancer treatment, leading to better outcomes. Although the exact safety of these dietary changes in humans isn't fully detailed, they are usually well-tolerated. These changes focus on using food to improve health, which is generally safe for most people.12345
Why are researchers excited about this trial?
Researchers are excited about this trial because it explores the impact of dietary changes on breast cancer risk. Unlike traditional treatments such as surgery, chemotherapy, or radiation, this approach focuses on dietary intervention as a preventive measure, potentially reducing inflammation that may contribute to cancer development. This trial aims to uncover how certain foods might influence cancer risk, providing a non-invasive, lifestyle-based strategy that could complement existing treatments and improve overall health. The potential to empower individuals to actively participate in their health management through diet is a compelling aspect of this research.
What evidence suggests that this dietary intervention is effective for reducing breast cancer risk?
Studies have shown that diet can significantly affect the risk of breast cancer and its recurrence. For instance, research indicates that reducing fat intake might lower the chances of breast cancer returning. One study suggested that dietary changes could improve the quality of life for those at risk of or dealing with breast cancer. Additionally, long-term dietary changes have been linked to a small decrease in breast cancer cases and deaths, though this was not statistically significant. Overall, these findings support the idea that diet could impact breast cancer risk. Participants in this trial will undergo physical exams and complete questionnaires to assess the impact of dietary habits on breast cancer risk.16789
Who Is on the Research Team?
Sagar D Sardesai, MSPH, PhD
Principal Investigator
Ohio State University Comprehensive Cancer Center
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants complete baseline physical measurements and dietary assessments using the Diet History Questionnaire III
Longitudinal Monitoring
Participants complete physical measurements every 6 months and questionnaires annually for 5 years
Extended Follow-up
Participants are followed up annually in years 5-10 to monitor long-term outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Dietary Intervention
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Patients complete physical measurements every 6 months and complete questionnaires annually for 5 years. Patients are followed up annually in years 5-10.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University Comprehensive Cancer Center
Lead Sponsor
Citations
Dietary Interventions for Breast Cancer Prevention
Their study highlighted that dietary patterns significantly impacted both the risk of BC recurrence and the overall quality of life.
Dietary fat reduction and breast cancer outcome
The study determined that low-fat dietary interventions can influence body weight and decrease breast cancer recurrence.
Dietary interventions in cancer: a systematic review of all ...
In this systematic review, we assessed all randomized controlled trials (RCTs) investigating dietary interventions for cancer patients.
Dietary Modification and Breast Cancer Mortality: Long-Term ...
During 8.5 years of dietary intervention, breast cancer incidence and deaths as a result of breast cancer were nonsignificantly lower in the intervention group, ...
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acsjournals.onlinelibrary.wiley.com
acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.35043What are the most effective exercise, physical activity and ...
This systematic review and network meta-analysis aimed to identify the most effective exercise, physical activity, and dietary interventions to reduce fat mass ...
A Low-Insulinemic Dietary Intervention to Reduce Breast ...
We will determine if a low-insulinemic dietary pattern intervention is feasible and effective in reducing breast cancer risk in high-risk women. Detailed ...
Effects of dietary intervention on human diseases
These results suggest that dietary interventions may be promising for improving cancer treatment outcomes. Accumulating data suggest that ...
Nutrition and Breast Cancer: A Literature Review on ...
The results of this prospective study indicate that a high-saturated-fat diet increases risk of BC and, most conspicuously, of receptor-positive cancer, ...
Dietary interventions and tumor response to chemotherapy ...
This review highlights the areas for further research to increase opportunities for nutritional-based interventions as adjuvant to chemotherapy for breast ...
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