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Diffusion-weighted imaging magnetic resonance imaging for Squamous Cell Carcinoma
N/A
Waitlist Available
Led By Gloria J Guzman Pérez-Carrillo, M.D.
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2-3 weeks post-standard of care treatment
Awards & highlights
Study Summary
This trial will use a new imaging technique to more accurately detect cancer recurrence and early non-responders to therapy in patients with squamous cell carcinoma of the neck.
Eligible Conditions
- Squamous Cell Carcinoma
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2-3 weeks post-standard of care treatment
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2-3 weeks post-standard of care treatment
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Apparent diffusion coefficient lowest value in a tumor (ADCmin)
Apparent diffusion coefficient mean (ADCmean)
Secondary outcome measures
Number of non-responders to treatment as measured by DWI MRI as compared to the number of non-responders to treatment as measured by FDG PET/CT
Trial Design
1Treatment groups
Experimental Treatment
Group I: DWI MRIExperimental Treatment1 Intervention
-The patients will undergo an optimized research neck DWI MRI, up to 3 weeks post-treatment and then a standard-of-care 3-month post-treatment FDG PET/CT examination.
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Who is running the clinical trial?
Washington University School of MedicineLead Sponsor
1,944 Previous Clinical Trials
2,304,485 Total Patients Enrolled
Gloria J Guzman Pérez-Carrillo, M.D.Principal InvestigatorWashington University School of Medicine
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You have not undergone a standard PET/CT scan as part of your medical care.You have implanted devices that are not safe for MRI scans.You have a strong fear of enclosed spaces.
Research Study Groups:
This trial has the following groups:- Group 1: DWI MRI
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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